Any choices not listed on this page don't have a major impact on the over-arching story. You can use this page to cross-reference or plan your approach in your save - and understand what actions are going to have the most wide-reaching consequences. On this page, we break down every major choice in the Mass Effect trilogy that severely impacts the story and carries from one game to the next.
All of this is retained, of course, in the newly remastered Mass Effect Legendary Edition - except now, it's all in one handy package. Now, it's true that much of this choice and consequence is simply smoke and mirrors say you kill one character and their role in the next game is still present, just replaced by a slightly-different character - but ultimately many of these decisions do add up to make for a satisfying and unique-feeling experience across all three games in the series. If the Mass Effect Trilogy is famous for anything, it's for its use of choices and consequences, where there's a great range of decisions for players to make throughout the series, with decisions having repercussions not just in the game where you make them, but also often in recurring storylines across all three games.